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Image Search Results
Journal: Journal of Extracellular Vesicles
Article Title: NK Cell‐Derived Small Extracellular Vesicles Armed With CLDN4‐Targeting Peptides Potentiate Radiotherapy in Gastric Cancer
doi: 10.1002/jev2.70200
Figure Lengend Snippet: ROS induction and radiosensitising effects of NESC in NCI‐N87 cells. (a) Western blot analysis of perforin, granzyme B and FasL in NK cell lysate and NK‐sEV. (b) Cell viability of NCI‐N87 cells incubated with three concentrations of NK‐sEVs or NESC (5, 10 and 20 µg). Viability of PBS‐treated cells was considered as a base value. Data was shown as mean ± s.d. ( n = 3). (c) Bar plot showing the KEGG enrichment analysis results, including the pathway names, related genes and pathway classifications. (d and f) Confocal images (f) and quantified data (d) of ROS generation in NCI‐N87 cells treated with different regimens. (blue: DAPI, green: DCFH‐DA). (e and g) Confocal images (g) and quantified data (e) of DNA breaks in NCI‐N87 cells treated with different regimens. (blue: DAPI, red: γ‐H2AX). G1: PBS, G2: NESC (200 µg/mL), G3: 2 Gy and G4: NESC (200 µg/mL) + 2 Gy. p values were calculated by an unpaired t ‐test (* p < 0.05, ** p < 0.01).
Article Snippet:
Techniques: Western Blot, Incubation